Details for gene set NCI_TRAIL SIGNALING PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	set02_ATM_minus_versus_BT_ATM_minus
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	NCI_TRAIL SIGNALING PATHWAY
Enrichment Score (ES)	-0.4145497
Normalized Enrichment Score (NES)	-1.9449722
Nominal p-value	0.0
FDR q-value	0.025457771
FWER p-Value	0.22

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	IL2RA	15	4.747	0.0111	No
2	NUP214	64	3.714	0.0181	No
3	LCK	137	3.203	0.0228	No
4	PPP3CB	153	3.144	0.0299	No
5	ITCH	197	2.938	0.0352	No
6	SOS1	370	2.483	0.0334	No
7	CSNK2A1	381	2.459	0.0391	No
8	PRKCA	397	2.430	0.0444	No
9	CASP3	413	2.406	0.0497	No
10	MAPKAP1	418	2.399	0.0555	No
11	MAP3K7	448	2.353	0.0600	No
12	AP2M1	478	2.309	0.0644	No
13	DAPP1	486	2.292	0.0698	No
14	CREBBP	519	2.250	0.0739	No
15	PRKDC	584	2.174	0.0764	No
16	PTEN	596	2.163	0.0812	No
17	YWHAZ	622	2.135	0.0854	No
18	RPS6KB1	706	2.046	0.0867	No
19	IL5	751	2.009	0.0896	No
20	GSK3B	765	1.997	0.0940	No
21	PIK3CA	824	1.937	0.0961	No
22	EIF4E	1119	1.747	0.0869	No
23	CTLA4	1130	1.742	0.0908	No
24	MAPK8	1169	1.724	0.0933	No
25	EEF2	1317	1.647	0.0906	No
26	CAMK4	1351	1.628	0.0931	No
27	SYK	1418	1.598	0.0941	No
28	PTPRC	1419	1.597	0.0980	No
29	GZMB	1463	1.577	0.1000	No
30	YWHAE	1550	1.540	0.0998	No
31	MAPK1	1594	1.523	0.1016	No
32	TRAF6	1621	1.510	0.1042	No
33	CSNK1A1	1654	1.498	0.1064	No
34	ARHGEF6	1736	1.469	0.1064	No
35	CFL2	1742	1.467	0.1098	No
36	PAG1	1777	1.449	0.1118	No
37	TBC1D4	1837	1.420	0.1126	No
38	TNFSF10	1870	1.406	0.1146	No
39	PIK3R1	2157	1.312	0.1047	No
40	MDM2	2278	1.267	0.1023	No
41	PTPRK	2458	1.209	0.0970	No
42	PRKCE	2610	1.173	0.0930	No
43	POU2F1	2833	1.121	0.0855	No
44	TOP1	3099	1.061	0.0759	No
45	RAN	3501	0.968	0.0599	No
46	HSP90AA1	3539	0.961	0.0605	No
47	PPP3CA	3559	0.957	0.0620	No
48	IGF1	3560	0.957	0.0644	No
49	PDPK1	3608	0.947	0.0646	No
50	TIAM1	3877	0.895	0.0545	No
51	PIM1	3908	0.888	0.0553	No
52	ERC1	3923	0.885	0.0568	No
53	AKT1S1	3957	0.880	0.0575	No
54	SATB1	3979	0.876	0.0587	No
55	MALT1	4026	0.868	0.0587	No
56	CD22	4047	0.864	0.0600	No
57	CRADD	4268	0.828	0.0519	No
58	KPNB1	4321	0.818	0.0515	No
59	GSK3A	4436	0.796	0.0482	No
60	BAD	4507	0.786	0.0470	No
61	PDE3B	4535	0.780	0.0476	No
62	AKT3	4594	0.772	0.0469	No
63	ETS1	4712	0.754	0.0434	No
64	AKT1	4977	0.711	0.0330	No
65	UBE2D3	4979	0.711	0.0347	No
66	RASA1	5023	0.704	0.0344	No
67	INSR	5132	0.691	0.0312	No
68	CAMK2G	5399	0.649	0.0205	No
69	EP300	5873	0.578	0.0001	No
70	FASLG	5895	0.575	0.0006	No
71	NFATC3	5945	0.567	-0.0003	No
72	IL4	5986	0.560	-0.0007	No
73	CDKN1A	6257	0.518	-0.0119	No
74	CHUK	6349	0.506	-0.0148	No
75	PDGFA	6424	0.496	-0.0170	No
76	BAX	6537	0.482	-0.0210	No
77	CDKN2A	6992	0.421	-0.0409	No
78	ASAH1	7016	0.418	-0.0409	No
79	E2F1	7467	0.357	-0.0608	No
80	CYCS	7517	0.351	-0.0622	No
81	XPO1	7628	0.335	-0.0664	No
82	CDK4	7918	0.298	-0.0790	No
83	FKBP8	8018	0.285	-0.0829	No
84	RPS6	8236	0.256	-0.0922	No
85	KPNA1	8239	0.256	-0.0917	No
86	PPARG	8381	0.235	-0.0976	No
87	FGR	8504	0.217	-0.1027	No
88	LRDD	8832	0.171	-0.1174	No
89	MAP3K1	8906	0.161	-0.1203	No
90	RAP1A	9206	0.119	-0.1338	No
91	TNFRSF1A	9263	0.111	-0.1361	No
92	DIABLO	9521	0.071	-0.1478	No
93	IL3	9524	0.071	-0.1477	No
94	TNFRSF10B	9656	0.050	-0.1537	No
95	BTK	9783	0.031	-0.1594	No
96	CTSD	9890	0.014	-0.1643	No
97	CALM2	10266	-0.045	-0.1814	No
98	EGR4	10291	-0.048	-0.1824	No
99	BLNK	10309	-0.050	-0.1831	No
100	APAF1	10407	-0.066	-0.1874	No
101	LMNB1	10486	-0.076	-0.1908	No
102	CASP1	10532	-0.083	-0.1927	No
103	EGF	10831	-0.129	-0.2061	No
104	AKAP5	10935	-0.146	-0.2105	No
105	IRS1	11122	-0.170	-0.2187	No
106	RAF1	11386	-0.204	-0.2303	No
107	NRAS	11559	-0.223	-0.2377	No
108	HRAS	11684	-0.237	-0.2428	No
109	AP2A1	12279	-0.305	-0.2695	No
110	TRAF2	12318	-0.311	-0.2704	No
111	LMNB2	12514	-0.335	-0.2786	No
112	SLC2A4	12634	-0.349	-0.2832	No
113	PPP5C	12697	-0.355	-0.2852	No
114	POU2F2	12770	-0.364	-0.2876	No
115	TBX21	12958	-0.386	-0.2953	No
116	RHEB	13014	-0.393	-0.2969	No
117	BLK	13045	-0.396	-0.2973	No
118	MAP3K8	13234	-0.417	-0.3049	No
119	KRAS	13393	-0.438	-0.3111	No
120	ARF5	13414	-0.441	-0.3109	No
121	SMPD1	13543	-0.455	-0.3157	No
122	SRC	13765	-0.482	-0.3247	No
123	BIRC2	14071	-0.516	-0.3375	No
124	TRADD	14236	-0.537	-0.3437	No
125	RNF128	14244	-0.538	-0.3427	No
126	CSF2	14405	-0.557	-0.3487	No
127	REL	14487	-0.568	-0.3510	No
128	ARFIP2	14492	-0.569	-0.3498	No
129	SPHK2	14517	-0.572	-0.3495	No
130	YES1	14598	-0.581	-0.3517	No
131	MAP2K4	14640	-0.588	-0.3522	No
132	ELK1	14948	-0.623	-0.3648	No
133	PLCG2	14956	-0.624	-0.3635	No
134	YWHAQ	15062	-0.634	-0.3668	No
135	CALM1	15082	-0.637	-0.3661	No
136	IFNG	15303	-0.665	-0.3746	No
137	DOK1	15319	-0.668	-0.3736	No
138	MAPK3	15401	-0.677	-0.3757	No
139	RIPK2	15580	-0.698	-0.3822	No
140	SMPD3	15637	-0.706	-0.3830	No
141	TSC2	15645	-0.708	-0.3816	No
142	PAWR	15663	-0.710	-0.3806	No
143	EIF4EBP1	15826	-0.732	-0.3862	No
144	PPP2R5D	16006	-0.758	-0.3926	No
145	MAP2K2	16032	-0.762	-0.3919	No
146	FADD	16038	-0.763	-0.3902	No
147	PLD2	16134	-0.775	-0.3927	No
148	ZAP70	16176	-0.781	-0.3926	No
149	CASP8	16284	-0.795	-0.3956	No
150	CFLAR	16298	-0.798	-0.3942	No
151	FOSL1	16325	-0.800	-0.3934	No
152	INPPL1	16331	-0.801	-0.3916	No
153	IBTK	16362	-0.806	-0.3910	No
154	CD40LG	16375	-0.807	-0.3896	No
155	NFKBIA	16391	-0.809	-0.3882	No
156	HCK	16436	-0.815	-0.3882	No
157	YWHAB	16464	-0.818	-0.3875	No
158	ARF1	16466	-0.818	-0.3855	No
159	SREBF1	16535	-0.827	-0.3865	No
160	CD79B	16562	-0.830	-0.3857	No
161	MAP3K14	16757	-0.855	-0.3925	No
162	RIPK1	16874	-0.871	-0.3957	No
163	CASP4	16907	-0.877	-0.3950	No
164	ARF6	16953	-0.884	-0.3949	No
165	PTGS2	17046	-0.900	-0.3969	No
166	GATA3	17055	-0.902	-0.3950	No
167	AKT2	17075	-0.904	-0.3936	No
168	BIRC3	17339	-0.944	-0.4034	No
169	MAPK9	17448	-0.962	-0.4060	No
170	RHOA	17480	-0.969	-0.4050	No
171	RELA	17566	-0.984	-0.4065	No
172	PRKACA	17631	-0.996	-0.4070	No
173	YWHAH	17687	-1.006	-0.4070	No
174	CD19	17851	-1.031	-0.4120	Yes
175	PRKRA	17878	-1.038	-0.4106	Yes
176	BID	17883	-1.039	-0.4082	Yes
177	ARFGAP1	17885	-1.039	-0.4057	Yes
178	DFFA	17956	-1.052	-0.4063	Yes
179	PARP1	18005	-1.059	-0.4059	Yes
180	DGKA	18084	-1.073	-0.4068	Yes
181	JUN	18099	-1.076	-0.4048	Yes
182	SHC1	18103	-1.076	-0.4022	Yes
183	CDKN1B	18144	-1.082	-0.4014	Yes
184	PLCG1	18203	-1.093	-0.4013	Yes
185	CASP2	18290	-1.111	-0.4026	Yes
186	MKNK1	18366	-1.127	-0.4032	Yes
187	EIF4A1	18503	-1.154	-0.4066	Yes
188	VAV2	18616	-1.178	-0.4089	Yes
189	BCL2	18625	-1.179	-0.4063	Yes
190	ATM	18685	-1.190	-0.4061	Yes
191	EIF4G1	18692	-1.193	-0.4034	Yes
192	GRB2	18879	-1.237	-0.4089	Yes
193	NFKBIB	18902	-1.241	-0.4068	Yes
194	PLEKHA2	18909	-1.243	-0.4040	Yes
195	IKBKG	18928	-1.246	-0.4017	Yes
196	CYLD	18965	-1.255	-0.4003	Yes
197	GAS2	19048	-1.271	-0.4009	Yes
198	CASP9	19125	-1.289	-0.4012	Yes
199	DFFB	19145	-1.295	-0.3989	Yes
200	PRKAB1	19264	-1.327	-0.4010	Yes
201	PRKCQ	19298	-1.339	-0.3992	Yes
202	TNF	19341	-1.351	-0.3978	Yes
203	RAC1	19377	-1.360	-0.3960	Yes
204	GOSR2	19461	-1.383	-0.3964	Yes
205	TSC1	19466	-1.385	-0.3931	Yes
206	CALM3	19591	-1.421	-0.3953	Yes
207	DAP3	19633	-1.434	-0.3937	Yes
208	BAG4	19659	-1.443	-0.3912	Yes
209	TP53	19687	-1.455	-0.3889	Yes
210	CD4	19717	-1.467	-0.3865	Yes
211	TNFAIP3	19726	-1.471	-0.3833	Yes
212	PTK2	19751	-1.476	-0.3807	Yes
213	ITK	19776	-1.489	-0.3781	Yes
214	APP	19814	-1.503	-0.3761	Yes
215	FKBP1A	19825	-1.506	-0.3728	Yes
216	GGA3	19827	-1.506	-0.3691	Yes
217	COPA	19881	-1.521	-0.3678	Yes
218	MYC	19912	-1.534	-0.3653	Yes
219	VAV1	19995	-1.568	-0.3652	Yes
220	KSR1	20065	-1.594	-0.3644	Yes
221	ACTA1	20070	-1.597	-0.3606	Yes
222	SFN	20083	-1.603	-0.3572	Yes
223	FYN	20107	-1.612	-0.3543	Yes
224	IKBKB	20132	-1.623	-0.3513	Yes
225	CASP6	20177	-1.642	-0.3493	Yes
226	PPP3CC	20266	-1.683	-0.3492	Yes
227	PRKCZ	20308	-1.703	-0.3468	Yes
228	SLC3A2	20423	-1.750	-0.3477	Yes
229	MAP2K1	20473	-1.779	-0.3456	Yes
230	PRKCD	20514	-1.805	-0.3429	Yes
231	LIMK1	20601	-1.848	-0.3423	Yes
232	FRAP1	20627	-1.863	-0.3388	Yes
233	MAF	20636	-1.867	-0.3346	Yes
234	PTPN1	20769	-1.947	-0.3358	Yes
235	CLTA	20840	-1.992	-0.3341	Yes
236	MEF2D	20891	-2.028	-0.3314	Yes
237	NFKB1	20944	-2.065	-0.3286	Yes
238	FBXW11	20996	-2.114	-0.3257	Yes
239	CLTB	21066	-2.158	-0.3235	Yes
240	NUMA1	21077	-2.170	-0.3186	Yes
241	MAPK14	21120	-2.209	-0.3150	Yes
242	BCL10	21159	-2.247	-0.3112	Yes
243	ARHGEF7	21179	-2.271	-0.3064	Yes
244	ARRB2	21227	-2.318	-0.3028	Yes
245	FOXP3	21314	-2.435	-0.3008	Yes
246	CARD11	21330	-2.461	-0.2953	Yes
247	PRF1	21361	-2.499	-0.2905	Yes
248	GBF1	21377	-2.528	-0.2849	Yes
249	PLEKHA1	21384	-2.541	-0.2789	Yes
250	ARHGDIB	21394	-2.566	-0.2729	Yes
251	CD72	21419	-2.609	-0.2675	Yes
252	SH3BP5	21431	-2.642	-0.2615	Yes
253	JUNB	21440	-2.670	-0.2552	Yes
254	CBLB	21453	-2.694	-0.2491	Yes
255	GSN	21499	-2.780	-0.2442	Yes
256	CASP7	21563	-2.954	-0.2398	Yes
257	PTPN6	21597	-3.085	-0.2336	Yes
258	NFKB2	21615	-3.137	-0.2266	Yes
259	CD79A	21671	-3.365	-0.2208	Yes
260	YWHAG	21678	-3.403	-0.2126	Yes
261	FCGR2B	21689	-3.450	-0.2045	Yes
262	CSK	21693	-3.473	-0.1960	Yes
263	PRKCH	21736	-3.724	-0.1887	Yes
264	NFATC2	21737	-3.736	-0.1794	Yes
265	MAP4K4	21744	-3.794	-0.1702	Yes
266	RELB	21749	-3.826	-0.1609	Yes
267	IRF4	21795	-4.216	-0.1525	Yes
268	LMNA	21836	-4.610	-0.1429	Yes
269	BCL3	21865	-4.977	-0.1318	Yes
270	NFATC1	21871	-5.174	-0.1192	Yes
271	VIM	21890	-5.636	-0.1060	Yes
272	FOS	21917	-6.478	-0.0911	Yes
273	NR4A1	21923	-6.633	-0.0748	Yes
274	EGR1	21942	-8.847	-0.0537	Yes
275	EGR3	21943	-9.744	-0.0294	Yes
276	EGR2	21944	-11.902	0.0001	Yes